- Worked as a driver and bodyguard for Mae West.
- Won 24 of his last 25 boxing matches.
- Was a friend of Frank Sinatra and appeared in 5 of his movies.
- Defeated World Middleweight Champion Vince Dundee.
- Defeated World Middleweight Champion Lou Brouillard in 1932.
- Defeated World Welterweight Champion Tommy Freeman in 1927.
- The Ring Boxing Magazine called Indrisano the "uncrowned world champion".
- He was married to Mary Dorothea Vardaro in the 1930s. He left Mary and their only child, Kathleen, living in the East Boston house of his mother (Maria Barrasso, the widow of Pietro Indrisano). John pursued a career in the film industry at this time and had a long-standing relationship with Mae West. He did not ask Mary for a divorce until late in the 1930s. One of John's grandchildren, Joan Vardaro McMillan, is a creative nonfiction writer, working on a memoir which includes her grandfather.
- His only child, Kathleen Joan Indrisano (married name: Kathleen McMillan), died on December 23rd, 2007, of renal failure. Kathleen was 75 years old. She had lived the final years of her life in the Indrisano family home in East Boston and was laid to rest in Holy Cross Cemetery, Malden, Massachusetts, with her paternal grandparents.
- Defeated future actor Canada Lee on August 14, 1931 in 10 rounds.
- Had a professional boxing record of 64-9-4 with 13 knockout victories.
- On November 14, 1927 he was knocked out in one round by Cyde Hull and suffered a broken jaw.
- He was the stunt coordinator for The Great John L. (1945) and later was featured in a 1953 episode of You Asked for It (1950) in which he portrayed the champion boxer John L. Sullivan in a recreation of the Sullivan/La Savant fight in Paris.
- Lost his first pro boxing matches, but ended his career winning 24 of his last 25 fights.
- Boxed professionally from 1923-1934.
- Defeated Vearl Whitehead at Legion Stadium in Hollywood, California in 10 rounds on 16 March 1934, and retired .
- Began his professional boxing career as Johnny Andrews and was undefeated in 27 fights.
- In 1922 won the New England Amateur Boxing Championship in the 115-125lbs. Division.
- Scored knockouts over such fighters as Walter Riley, Tommy Flanagan, Arthur Goslin, and Steve Gotch.
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