- One of the reasons he went from being a Paramount executive to a producer is because of his drug use. Once, he reportedly passed out during a meeting.
- He was reportedly very well read about the history of the movie business. He could stand at a spot in Los Angeles and recite something historic that happened there.
- He was portrayed as a sinister frequent call girl abuser in the book "You'll Never Make Love in This Town Again" by four ex-call girls (Liza, Robin, Tiffany and Linda).
- Helped one of his bodyguards, Vic Manni, start his acting career. Simpson hired Manni after he was threatened by the mafia.
- On January 19, 1996, Simpson was found dead in the bathroom of his Bel Air, Los Angeles home. His death was initially attributed to "natural causes". An autopsy and toxicology report later determined that Simpson had died of heart failure caused by combined drug intoxication (cocaine and prescription medications). At the time of his death, there were 21 different drugs in his system, including antidepressants, stimulants, sedatives, and tranquilizers. In August 1996, investigative reporter Chuck Philips of the Los Angeles Times revealed that Simpson had been obtaining large quantities of prescription drugs from 15 different doctors, and that police found 2,200 prescription pills lined up in alphabetical order in his bedroom closet.
- Had a talent for deciphering key on-screen moments in a script. Moments in a wide-release picture known as 'The Hollywood Moment'.
- Dabbled in Scientology during the 1970s and eventually left after having squandered $25K on the church.
- Member of the Phi Delta Theta Fraternity, University of Oregon, 1969
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