Her talent for playing piano was discovered by the film director Shunji Iwai when she was seven years old.
In the April 2005, she debuted as a voice actress, starring as heroine Sakura in Tsubasa Chronicle and recording several songs for its soundtrack.
She released her debut album, Tenkyu no Ongaku on 6 December 2006.
She took up piano at the age of four.
She made her debut as a singer in 2005 with "Omna Magni", produced by Yoko Kanno. It was used as the ending theme song for the anime Sousei no Aquarion.
She released "Amrita", the ending song for the Tsubasa Chronicle film, as well as "Undine", the opening theme for the TV Tokyo anime Aria the Animation, coupled with its inserted song "Symphony". It achieved No. 25 on the Oricon chart.
She graduated from Tokyo College of Music as piano major with the top score in her senior year.
From the age of 8 to 17, she played piano solos for three of his films: Love Letter, All About Lily Chou-Chou and Hana and Alice.
In 2007, she was invited to represent Japan at the Japan-China cultural exchange event.
In 2006, Makino released two songs from another TV Tokyo anime, Aria the Natural, the theme song "Euphoria" and insert song "Amefuribana". They were released on one product and achieved No. 18 on the Oricon chart.