In the movie drama with songs, The Man I Love (1946), Peg La Centra dubbed the singing voice of Ida Lupino. In this film the following year, Miss Lupino did her own singing.
The scenes in the roadhouse's bowling alley were shot at a real alley located near the studio.
Ida Lupino was paid $95,000 for her role.
In a 1969 interview, director Jean Negulesco recalled that when Fox studio chief Darryl F. Zanuck gave him the assignment to direct 'Road House', Zanuck told him, "This is a bad script. Three directors have refused it. They don't know what they're doing, because basically it's quite good. Remember those pictures we used to make at Warner Bros., with Pat O'Brien and Jimmy Cagney, in which every time the action flagged we staged a fight and every time a man passed a girl she'd adjust her stocking or something, trying to be sexy? That's the kind of picture we have to have with 'Road House.'"
Three of the people involved in this production - studio head Darryl F. Zanuck, director Jean Negulesco and star Ida Lupino - had previously worked for Warner Bros. In fact, despite the commercial success of his last Warners film, Johnny Belinda (1948), Negulesco had just been fired from Warners when Zanuck signed him to Fox and offered him 'Road House'.