This short was created by the Warner animation team right after finishing "What's Opera, Doc?" That short took seven weeks to finish, but Warner allotted only 5 weeks to create any cartoon short. To cover up for it, Chuck Jones had the animation team doctor their time cards to state they were working on this short, when they were actually finishing up "What's Opera, Doc?". The team knew that Road Runner/Wile E. Coyote shorts were so by-the-numbers they could easily finish up the short in three weeks.
The soundtrack from the short was performed in the concert series "Bugs Bunny on Broadway".
At the end of the film, Wile E. Coyote is exhausted and the Road Runner gets an opportunity to finish him off. The bird instead shows him mercy, and explains in writing "I just don't have the heart". This is a rare occasion where the focus is on the Road Runner's characterization, instead of Wile's.
The gag where the camera pans up to the chute and when the coyote lights up the bomb, it explodes immediately, is Linda Jones Clough's (daughter of Chuck Jones) favorite gag.
A stately Saguaro cactus is seen here a few times, in full bloom. The flowers appear at the tip of each cactus arm, as shown, and attract both avian and insect pollinators.