This is a pretty typical piece of Sci-Fi tripe of the late 50's-early 60's period. With the assistence of the Skipper (Yep, Alan Hale) two scientists track down a rougue body part that takes over the mind of a local teen, Paul. The hand controls him through some "cosmic force" that goes unexplained. The hand/arm strangles the poor lad's toadlike landlady before taking over his mind. Paul is less successful in killing people, as he fails to kill both a sour soda shop keeper and his Swedish girlfriend.
Will Paul be able to defeat his foe? Or will he need the help of alley cats? "Dames like this ALWAYS got beer around".