Near the beginning of the film, Jonathan Brandis' character Matthew calls Rodney Dangerfield's character Chester, "Chesterfield." Brandis had a habit in real-life of referring to certain friends in jest by adding "field" to the end of their names. It is rumored by some who knew him that he carried this over into the film and ad-libbed "Chesterfield" as an inside joke.
The movie was originally going to film in Dallas, Texas but the location was changed to Denver, Colorado because of concerns about the effects of heat stress on child actors in Texas.
Whoopi Goldberg was given the option to either portray Julie in this movie or to take the lead role in Sister Act (1992). Although Goldberg loved Rodney Dangerfield and considered him a comedy icon, she chose the latter film because she felt it would be more successful. She proved right as Sister Act (1992) turned out to be one of the top 10 grossing films of 1992, while Ladybugs (1992) flopped at the box office.
The soccer games matches were filmed at three Colorado educational institutions. They were the Kent Denver School, Saint Mary's Academy, and the Aurauria Higher Education Center.