While the team tries to solve a murder tied to counterfeit wine, Mac Taylor from the New York crime lab comes to Las Vegas for his girlfriend's convention, only to discover that she has disappeared.
The team investigate a "locked room mystery" when a poker player is found murdered in an elevator, which he rode alone. Meanwhile, the search is on for a dominatrix who took a session too far.
While investigating the brutal homicide of a teenage motocross driver, the team stumbles upon a man and his daughter living in mysterious underground bunker.
The murder of a brother and sister and a pair of home invaders is part of a complex revenge plot, and a man is burned alive in the trunk of his own car.
The team uncovers a complex plot to rob a high-stakes Texas Hold-em game, but one of the co-conspirators may have been forced to participate against his will after his son was kidnapped.
The team gets a second crack at a reclusive millionaire who may have gotten away with murder 14 year earlier when a new dead body is found in his home.
A homeless man is found dead in an alley after suspiciously winning big at a casino, and CSI soon finds connections between the victim, two casino employees, and a local pawn shop.
Sara suspects CSI is dealing with Armenian terrorists when she discovers a bomb on a man found in a flood channel, and Greg is accused of planting evidence in an old case.
A spa weekend for Sara, Finlay and Morgan turns into a murder investigation and missing persons case when Finlay disappears, as the CSI team must piece together what happened in detail to find her.