Loosely based on the long running European comic by the same name.
Writer J. Michael Straczynski was so upset over the amount of control MGM had over production, that he declared that he would never work again with MGM under the current administration.
Teryl Rothery (who plays Jeremiah's mother) was in Stargate SG-1 (1997), where she played a character in-residence at the Cheyenne Mountain Complex, the same place in which the Western Alliance is centered (a.k.a. Thunder Mountain).
In a twisted turn of destiny, this series unexpectedly (and partially) predicted the 2020's Covid19 pandemic, 18 years before of it happened (a virus responsible of uncountable deaths in adult people but children are the lesser affected by the disease).