As of this episode, this is the final appearance of Anthony "Tony" Russo.
Having decided to move away, this marks the final appearance of Tony and his wife, Shelley Russo.
Blossom and Tony's scene in the kitchen is a callback to the pilot's final scene (and Tony's first appearance), where he drank coffee from the pot and had a chat with Blossom at the table. In the Season 4 flashback episode "Our Favorite Scenes," Michael Stoyanov said that scene from the pilot was his favorite.
Actor Michael Stoyanov left the series to become a writer for Conan O'Brien. He later said he regretted his decision.