Like The Skipper in Gilligan's Island Up at Bat, Madame Esmeralda mentions Frankenstein. But unlike Gilligan, she doesn't think she's turning into a bat.
During the segment on ICarly, Freddie plays a vampire. This is a reference to Gilligan's Island Up at Bat, where Gilligan plays a vampire in his dream.
Gilligan as vampire is referred to as the "bat man" and the climactic struggle features the on-screen comic book-style sound effects forever associated with Adam West's Batman.