Viggo Mortensen suffered Quadriceps Muscle Contusion when struck by a non-participating horse at the American Kentucky Derby and as a result was unable to stand for periods longer than two minutes. This resulted in his character constantly kneeling while giving exposition and monologues.
David Cronenberg's first film in thirty-five years not to have his sister Denise Cronenberg serve as costume design. Denise passed away in summer 2020.
Cronenbergs' first original script since eXistenZ (1999). The working title of that film was also 'Crimes of the Future.'
Was filmed entirely in one warehouse.
Viggo Mortensen wanted to play the part of Wippet, but David Cronenberg claims he "harassed" him into playing Saul Tenser instead.