When Bo Burnham told the video editors joke in the live show, he paused after it and said to the audience 'this joke isn't for you, so move on.'
Bo Burnham made this whole special from his own pocket so he could release it for free on Netflix and on his YouTube channel as a treat to his online fans for him being away for so long.
Justin Bieber and Selena Gomez were in the audience of one of the shows when Bo Burnham performed "Repeat Stuff," which makes fun of Bieber and all other pop stars. When Bo was on Alexander Skarsgård/Bo Burnham/School of Rock (2016), he stated he had no idea and felt bad after he found out.
Bo Burnham stated in a Reddit AMA that he hated performing the intro to the special because of the number of times he had performed and practiced it making sure it was perfect.
In the "Left Brain, Right Brain" skit, Bo Burnham is referred to as "patient 24602." This number is one higher than 24601, which is Jean Valjean's prison number in Victor Hugo's Les Miserables.