This anime is very realistic and does not shy away from bloody violence. It has a balance between action and drama. A must see. Soon as you are done with one episode you immediately want to see the next one. I am currently on episode 6 and just can not get enough. The title is a bit misleading. The series focuses on 5 girls and the handler/ brothers. A processes called conditioning can make the girls more cybernetic than human but the more the girls are conditioned the less time they have to live. Each girl's relationship with the handler / brother is shown how they treated by their brother. Some of them are treated as lap dogs, some as a job and some are treated well as a sister. The series has some very interesting characters and story lines.