The story of Orochi revolves around the life of the Monzen family. Aoi Monzen, a famous, but aging, movie star and Kazusa and Lisa Monzen her two daughters. Aoi hopes for them both to take over her legacy as a star, but Kazusa does not live up to her expectations. The mother is always pitting the girls against one another competitively. As a result, as the years pass, the love the sisters shared grows to a hidden hatred.

When another girl named Orochi saves the girl's mother from a terrible accident a bizarre chain of events is set in motion spanning many years. The atmosphere in their estate builds up until Orochi reveals a terrible truth that the family must keep hidden from the world. Orochi serves as the narrator of the story. The movie is based on a Kazuo Umezu manga series which ran from 1969 to 1970.